Innovative Technology to Produce Heart Valves from Tissues In-Lab

It is interesting to see how advanced medical technology has become and there is a solution for even the most complicated conditions. Tissue repair and engineering has helped in biological repair and development of several medical devices. It is now possible to reduce cardiovascular complications and diseases by production of valves through tissue.

Commercial production of valve to treat cardiovascular problems

Before years back, it would be an impossible thought to produce valve tissue and use it as replacement. However, with innovative research and cutting-edge technology, the TAVR & TAVI contract manufacturing can produce replacement for transcatheter aortic valve and mitral valve. These values are important for proper functioning of the heart as they prevent the backflow of the blood and prevent blood leakage.

The production of TMVR and TAVR is important as it helps in treating conditions like mitral regurgitation. If the valves are not replaced, it can cause adverse impact like increase in the blood volume and pressure leading to increase in buildup of fluid within the lungs. For a company to produce and commercialize the device, the valve production is important.

Choosing the right contractor for valve production

When it comes to production of the valve, there are many aspects that need to be taken care. The tissue which will be use must be biocompatible and allow production of a valve that is fully functional. It is important to choose the right consultant with expertise and professional experience.

· Cutting edge research lab and in-depth knowledge about production of transcatheter heart valves.

· Extensive need for in-hand experience about tissue and valve production.

· Testing biocompatibility of the valves for use with the heart to eliminate complication.

· Certified commercial contractor with production abiding standard protocol under regulatory guidelines.

Tissue production for treating injuries and damage

The sourcing of the tissue along with its production is an important aspect to consider. In most of the tissue patch development, bovine pericardium tissue is used. An experienced and professional contractor ensure that they take care of end to end development. The process starts with procuring the tissue from slaughterhouse. The tissue fixation process is done by research experts in labs and customized tissue patches are produced depending on the requirement.

The tissue for the valve or stent for every client is different and hence the production is based on customization. After the final valve from tissue is produced, it is sold to the client after a series of clinical trial. The process of clinical trial is important as it helps in establishing the function and performance by the valve developed from tissue patch.

For the manufacturing of TAVR and TMVR, it is important for a company to have their own wet lab. This is important for designing the tissue and studying different aspects. The lab must be equipped with solution for tissue fixation and proper storage facility. The solution required for preparation, sterility and storage must be used only after testing the quality. With such innovative techniques, development of tissue for valve production is easy and can help in keeping heart healthy.